Doctor Octopus

A highly intelligent mad scientist,  Otto Octavius is one of Spider-Man’s greatest enemies.  Eventually becoming terminally ill,  Doctor Octopus was able to transfer his mind into Peter Parker’s body,  becoming the Superior Spider-Man.

First Appearance:  Amazing Spider-Man #3 (1963)
Creators:  Stan Lee,  Steve Ditko
Powers:  Tentacles,  Wall-Crawling,  Superhuman Strength,  Speed,  Agility, Stamina,  and Reflexes,  Spider-Sense

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Issues

Black entries are ongoing series
Green entries are Limited series
Red entries are One-Shots
Orange are alternate universe stories
Blue is for comments

Reading Order

Alternate Starting Point:  Amazing Spider-Man #682

Amazing Spider-Man #3 – First appearance of Doctor Octopus

Spider-Man: Doctor Octopus: Year One #1 (2004)
Spider-Man: Doctor Octopus: Year One #2
Spider-Man: Doctor Octopus: Year One #3
Spider-Man: Doctor Octopus: Year One #4
Spider-Man: Doctor Octopus: Year One #5

Amazing Spider-Man #11
Amazing Spider-Man #12

Amazing Spider-Man Annual #1 (1964) – First appearance of the Sinister Six

Amazing Spider-Man #31 – First appearance of Gwen Stacy and Harry Osborne
Amazing Spider-Man #32
Amazing Spider-Man #33

Amazing Spider-Man #53
Amazing Spider-Man #54
Amazing Spider-Man #55
Amazing Spider-Man #56

Amazing Spider-Man #88
Amazing Spider-Man #89
Amazing Spider-Man #90

Amazing Spider-Man #112
Amazing Spider-Man #113
Amazing Spider-Man #114
Amazing Spider-Man #115

Amazing Spider-Man #130
Amazing Spider-Man #131

Fantastic Four #267

Amazing Spider-Man #334
Amazing Spider-Man #335
Amazing Spider-Man #336
Amazing Spider-Man #337
Amazing Spider-Man #338
Amazing Spider-Man #339

Spider-Man Unlimited #3

Untold Tales of Spider-Man #19

Marvel Adventures Spider-Man #15

Marvel Adventures Spider-Man #33

Amazing Spider-Man #682
Amazing Spider-Man #683
Amazing Spider-Man #684
Amazing Spider-Man #685
Amazing Spider-Man #686
Amazing Spider-Man #687

Amazing Spider-Man #697
Amazing Spider-Man #698
Amazing Spider-Man #699
Amazing Spider-Man #700

Superior Spider-Man #1 (2013)
Superior Spider-Man #2
Superior Spider-Man #3
Superior Spider-Man #4
Superior Spider-Man #5
Superior Spider-Man #6
Superior Spider-Man #7
Superior Spider-Man #8
Superior Spider-Man #9
Superior Spider-Man #10
Superior Spider-Man #11
Superior Spider-Man #12
Superior Spider-Man #13
Superior Spider-Man #14
Superior Spider-Man #15
Superior Spider-Man #16
Superior Spider-Man #17
Superior Spider-Man #18
Superior Spider-Man #19
Superior Spider-Man #20
Superior Spider-Man #21
Superior Spider-Man #22
Superior Spider-Man #23
Superior Spider-Man #24
Superior Spider-Man #25
Superior Spider-Man #26
Superior Spider-Man #27
Superior Spider-Man #28
Superior Spider-Man #29
Superior Spider-Man #30
Superior Spider-Man #31
Superior Spider-Man #32
Superior Spider-Man #33